Termine Fungiculture – A Hidden Treasure Trove
Termites and their symbionts
Studying the microbiome of social insects, such as termites, helps to identify new aspects of small-molecule mediated symbiotic relations. At the same time it serves platform to identify new antibacterial and antifungal agents.
Within this project, we aim to isolate, characterize and understand the role of natural products produced by microorganisms associated with fungus-growing termites. We used various different culturing techniques to isolate termite-associated microbes and pursued the whole genome sequence of several key isolates. Subsequent chemical analysis of our isolates in axenic and co-cultures revealed several new natural product classes showing a diverse set of biological activities.
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